Medical Director, Rheumatology
Company: Alumis Inc.
Location: South San Francisco
Posted on: July 8, 2025
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Job Description:
Alumis Inc. is a precision medicines company with the mission to
transform the lives of patients with autoimmune diseases. Even with
treatment innovations of the last two decades, many patients with
immunologic conditions continue to suffer - our goal is to
fundamentally change the outcomes for these patients. We are
seeking an experienced medical professional to serve as a Medical
Director, Rheumatology, reporting to the Vice President of Clinical
Development, Rheumatology. The successful individual will play a
pivotal role in advancing our clinical programs from Phase 2
through regulatory approval. You will contribute to the strategic
planning, execution, and management of the SLE program which
currently consists of a Phase 2b study (the LUMUS Trial) designed
to be the first of two pivotal studies with ESK-001 in SLE. ESK-001
is a highly selective TYK-2 inhibitor which has the potential to be
a best-in-class oral treatment for SLE. Collaborating closely with
cross-functional teams, this person will contribute to the
scientific and medical vision, and provide leadership in the
development of innovative therapies to address unmet medical needs
in SLE and related inflammatory conditions. RESPONSIBILITIES: ·
Serve as the Sponsor medical monitor for the LUMUS trial and
collaborate with CRO to provide monitoring oversight; · Review and
follow all SAEs; · Participate in in-stream data reviews; ·
Interact with PIs and site staff (e.g.: by raising and responding
to queries); · Draft key study documents (e.g.: responses to
Regulatory requests for information); · Work on the
cross-functional Study Execution Team for LUMUS and broadly across
Rheumatology Clinical Development programs at Alumis; · Contribute
to the design and development of clinical studies as well as other
cross-functional initiatives; · Has opportunities for external
engagement (e.g.: participation in Investigator Meetings, external
Data Monitoring Committee reviews, etc…); · Maintains the highest
levels of integrity and ethical standards for scientific inquiry in
drug development. QUALIFICATIONS AND SKILLS REQUIRED: · Licensed
physician (required); · Board certification in rheumatology or
related field (desired); · Industry experience in pharmacovigilance
or clinical development (helpful); · Ability to interact
effectively in a cross-functional setting; · Strong interpersonal
and communications skills (written and verbal) to effectively
address all levels within an organization; · Ability to assess,
understand, and communicate continuously expanding medical and
scientific information; · Ability to work across diverse teams in a
matrixed organizational structure, both as a leader and as part of
a cross-functional team; · Approaches deliverables in an organized
manner with attention to detail and is able to meet timelines in a
fast-paced environment; · Able to work productively with a high
level of independence. The salary range for this position is
$285,000 USD to $325,000 USD annually. This salary range is an
estimate, and the actual salary may vary based on the Company’s
compensation practices. This position is located in South San
Francisco, CA and employees are expected to be onsite
Tuesday-Thursday. Open to remote applicants with requirement to be
onsite once a month. Alumis Inc. is an equal opportunity employer.
Alumis compensation packages include generous stock option grants
for all employees as well as an annual bonus program. Other
benefits include: Health insurance premiums paid at 90% for
employee, 80% for dependents Free access to Genentech Bus & Ferry
Share program $100 monthly cell phone stipend Unlimited PTO for
Exempt employees Free onsite gym and a kitchen stocked with yummy
snacks and drinks! We are a hard-working, collaborative team on a
mission to transform patient’s lives and we aspire to elevate ,
challenge and nurture one another along the way.
Keywords: Alumis Inc., Watsonville , Medical Director, Rheumatology, Healthcare , South San Francisco, California
